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Extend the selection to the last cell down

Windows shortcut 
CtrlShift
Mac shortcut 

If the active cell is empty, Excel will extend the selection to the first non-empty cell below the active cell. If the active cell is non-empty, Excel will extend the selection on the last non-empty cell below the active cell. On a Mac, the command key (⌘) can be used instead of the control key.

Related videos

The videos below demonstrate this shortcut.
In this video, we'll look at how to apply conditional formatting to one cell based on values in another, using a formula.
Pivot Tables are fantastic tools for summarizing data, but you can also use formulas to build your own summaries using functions like COUNTIF and SUMIF. See how in this 3 minute video.
In this video, we'll look at a few ways to generate random values with the RANDBETWEEN function, including random dates, random prices, and random workdays.
In this video, we'll look at how to create a line chart in Excel to plot historical, 30-year mortgage interest rates.
In this video, we'll look at how to create 3D references, an elegant way to analyze multiple worksheets with simple formulas.