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Select active cell only

Windows shortcut 
ShiftBackspace
Mac shortcut 
Delete

When multiple cells are selected, this shortcut will leave only the active cell selected.

Related videos

The videos below demonstrate this shortcut.
In this lesson, we cover shortcuts you can use to move the active cell in a selection.
In this video, we'll look at how you can use the CHOOSE function. We also compare a formula based on CHOOSE vs. a formula based on VLOOKUP.
This video shows how to use VLOOKUP to merge data in two tables based on a common ID. You can even use this technique to reorder the columns you retrieve.
In this video, we'll plot American generations in a chart with floating bars. This seems like a simple problem, but a solution takes a little creative thinking.