Quick, clean, and to the point

Extend the selection to the last cell right

Windows shortcut 
Mac shortcut 

If the active cell is empty, Excel will extend the selection to the first non-empty cell to the right. If the active cell is non-empty, Excel will extend the selection on the last non-empty cell to the right. On a Mac, the command key (⌘) can be used instead of the control key.

Related videos

The videos below demonstrate this shortcut.
This video provides a brief introduction to structured references. Structured references are an easy way to refer to tables in Excel formulas.
In this lesson, we cover shortcuts you can use to extend selections.
In this video, we'll look at how to use conditional formatting to shade alternating groups of rows - groups of 3 rows, groups of 4 rows, and so on.
In this video, learn how to use VLOOKUP to build a simple form to extract employee information from a table, in about 3 minutes. VLOOKUP is a key Excel function.
In this video, we'll use MATCH to find the position of an item in a table, and the INDEX function to retrieve the value at that position in a two-way lookup.