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Insert or edit comment

Windows shortcut 
ShiftF2
Mac shortcut 
Fn⇧F2

This shortcut will open a comment that exists in the active cell, ready to edit. If there is no comment in the active cell, a new comment will be created.

222 Excel Shortcuts for Windows and Mac

Related videos

The videos below demonstrate this shortcut.
Shortcuts for editing cells
In this lesson, we review shortcuts you can use to edit cells more efficiently.